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Recombinant human Keratinocyte Growth Factor-2

KGF-2 is a member of the fibroblast growth factor (FGF) family. FGF family members possess broad mitogenic and cell survival activities, and are involved in a variety of biological processes, including embryonic development, cell growth, morphogenesis, tissue repair, tumor growth and invasion. FGF-10 exhibits mitogenic activity for keratinizing epidermal cells, but essentially no activity for fibroblasts, which is similar to the biological activity of FGF7. Studies of the mouse homolog of suggested that this gene is required for embryonic epidermal morphogenesis including brain development, lung morphogenesis, and initiation of lim bud formation. This gene is also implicated to be a primary factor in the process of wound healing.Keratinocyte Growth Factor-2 Human Recombinant produced in E.Coli is a single, non-glycosylated polypeptide chain containing 170 amino acids (40-208) and having a molecular mass of 19300 Dalton.

 

Biological Activity

Specific Activity of 2.0 x 106IU/mg.

Purity

Greater than 95.0% as determined by SDS-PAGE and SEC-HPLC.

Molar Mass

19.3 kDa

Source

Produced in E.coli. (Escherichia coli)

Physical Appearance

Sterile Filtered White lyophilized (freeze-dried) powder.

Solubility

It is recommended to reconstitute the lyophilized protein in sterile H2O.

Storage/Stability

Lyophilized protein should be stored at < -20℃, though stable at room temperature for 3 weeks.
Reconstituted protein solution can be stored at 4-7℃ for 2-7 days.
Aliquots of reconstituted samples are stable at < -20℃ for 3 months.

SDS-PAGE
SEC-HPLC