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Recombinant bone morphogenetic protein-2

Recombinant bone morphogenetic protein-2 is one of the members of the family of transforming growth factor beta super, has induced between undifferentiated mesenchymal stem cells into chondrocytes and osteoblasts directional differentiation and proliferation, and promote the osteoblast differentiation of mature, participated in the reconstruction of bone and cartilage growth and its process, thus accelerating bone defect repair. BMP - 2 body form before synthesis in the body, the proteases cut to remove signal peptide and the peptide,Mature peptide composed of 114 amino acid residues was obtained. The conserved structure of mature peptide was correctly folded by 7 pairs of disulfide bonds .

Purity

Greater than 95.0% as determined by SDS-PAGE .

Molar Mass

26 kDa

Source

Produced in Escherichia coli  (E.coli secretion technology).

Physical Appearance

Sterile Filtered White lyophilized (freeze-dried) powder.

Solubility

It is recommended to reconstitute the lyophilized protein in sterile H2O.

Storage/Stability

Lyophilized protein should be stored at < -20°C, though stable at room temperature for 3 weeks.
Reconstituted protein solution can be stored at 4-7°C for 2-7 days.
Aliquots of reconstituted samples are stable at < -20°C for 3 months.

SDS-PAGE